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» Comparison of Current BLAST Software on Nucleotide Sequences
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BMCBI
2006
132views more  BMCBI 2006»
13 years 7 months ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas
BMCBI
2002
134views more  BMCBI 2002»
13 years 7 months ago
CoreGenes: A computational tool for identifying and cataloging "core" genes in a set of small genomes
Background: Improvements in DNA sequencing technology and methodology have led to the rapid expansion of databases comprising DNA sequence, gene and genome data. Lower operational...
Nikhat Zafar, Raja Mazumder, Donald Seto
BMCBI
2004
154views more  BMCBI 2004»
13 years 7 months ago
Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments
Background: With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than ...
Ryan Brodie, Alex J. Smith, Rachel L. Roper, Vasil...
BMCBI
2007
139views more  BMCBI 2007»
13 years 7 months ago
Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
Background: RNA interference (RNAi) is a naturally occurring phenomenon that results in the suppression of a target RNA sequence utilizing a variety of possible methods and pathwa...
Andrew S. Peek
BMCBI
2007
106views more  BMCBI 2007»
13 years 7 months ago
Simultaneous identification of long similar substrings in large sets of sequences
Background: Sequence comparison faces new challenges today, with many complete genomes and large libraries of transcripts known. Gene annotation pipelines match these sequences in...
Jürgen Kleffe, Friedrich Möller, Burghar...