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BMCBI
2007
124views more  BMCBI 2007»
13 years 8 months ago
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
G. Traver Hart, Insuk Lee, Edward M. Marcotte
ECCC
2008
168views more  ECCC 2008»
13 years 8 months ago
Algebrization: A New Barrier in Complexity Theory
Any proof of P = NP will have to overcome two barriers: relativization and natural proofs. Yet over the last decade, we have seen circuit lower bounds (for example, that PP does n...
Scott Aaronson, Avi Wigderson
COLING
1996
13 years 9 months ago
Computational Complexity of Probabilistic Disambiguation by means of Tree-Grammars
This paper studies the computational complexity of disambiguation under probabilistic tree-grammars as in (Bod, 1992; Schabes and Waters, 1993). It presents a proof that the follo...
Khalil Sima'an
BMCBI
2007
88views more  BMCBI 2007»
13 years 8 months ago
Use of DNA melting simulation software for in silico diagnostic assay design: targeting regions with complex melting curves and
Background: DNA melting curve analysis using double-stranded DNA-specific dyes such as SYTO9 produce complex and reproducible melting profiles, resulting in the detection of multi...
John P. Rasmussen, Christopher P. Saint, Paul T. M...
BMCBI
2004
98views more  BMCBI 2004»
13 years 8 months ago
STING Millennium Suite: integrated software for extensive analyses of 3d structures of proteins and their complexes
Background: The integration of many aspects of protein/DNA structure analysis is an important requirement for software products in general area of structural bioinformatics. In fa...
Roberto H. Higa, Roberto C. Togawa, Arnaldo J. Mon...