Alternative splicing is an important mechanism for increasing protein diversity. However, its functional effects are largely unknown. Here, we present our new software workflow co...
Dorothea Emig, Nathan Salomonis, Jan Baumbach, Tho...
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
It is widely recognized that complexity of metabolic networks arises from duplication, recruitment and recombination of enzyme protein domains. However, variations of the domain ev...
It is widely accepted that complexity of biological systems arises from combinations of common subunits. In this work we investigate the combinatorial patterns of protein domains ...
Background: Metabolic pathway is a highly regulated network consisting of many metabolic reactions involving substrates, enzymes, and products, where substrates can be transformed...
Lei Chen, Kai-Yan Feng, Yu-Dong Cai, Kuo-Chen Chou...