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BMCBI
2007
135views more  BMCBI 2007»
13 years 9 months ago
UbiProt: a database of ubiquitylated proteins
Background: Post-translational protein modification with ubiquitin, or ubiquitylation, is one of the hottest topics in a modern biology due to a dramatic impact on diverse metabol...
Alexander L. Chernorudskiy, Alejandro Garcia, Euge...
BMCBI
2008
154views more  BMCBI 2008»
13 years 9 months ago
Extension of the COG and arCOG databases by amino acid and nucleotide sequences
Background: The current versions of the COG and arCOG databases, both excellent frameworks for studies in comparative and functional genomics, do not contain the nucleotide sequen...
Florian Meereis, Michael Kaufmann
BMCBI
2008
142views more  BMCBI 2008»
13 years 9 months ago
Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
BMCBI
2008
129views more  BMCBI 2008»
13 years 9 months ago
An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments
Background: Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for e...
Ari Rantanen, Juho Rousu, Paula Jouhten, Nicola Za...
BMCBI
2008
144views more  BMCBI 2008»
13 years 9 months ago
PDTD: a web-accessible protein database for drug target identification
Background: Target identification is important for modern drug discovery. With the advances in the development of molecular docking, potential binding proteins may be discovered b...
Zhenting Gao, Honglin Li, Hailei Zhang, Xiaofeng L...