UbiProt: a database of ubiquitylated proteins

Background: Post-translational protein modification with ubiquitin, or ubiquitylation, is one of the hottest topics in a modern biology due to a dramatic impact on diverse metabolic pathways and involvement in pathogenesis of severe human diseases. A great number of eukaryotic proteins was found to be ubiquitylated. However, data about particular ubiquitylated proteins are rather disembodied. Description: To fill a general need for collecting and systematizing experimental data concerning ubiquitylation we have developed a new resource, UbiProt Database, a knowledgebase of ubiquitylated proteins. The database contains retrievable information about overall characteristics of a particular protein, ubiquitylation features, related ubiquitylation and de-ubiquitylation machinery and literature references reflecting experimental evidence of ubiquitylation. UbiProt is available at http://ubiprot.org.ru for free. Conclusion: UbiProt Database is a public resource offering comprehensive informa...

• Type: Journal
• Year: 2007
• Where: BMCBI
• Authors: Alexander L. Chernorudskiy, Alejandro Garcia, Eugene V. Eremin, Anastasia S. Shorina, Ekaterina V. Kondratieva, Murat R. Gainullin
• Keywords: BMCBI 2007, Particular Ubiquitylated Proteins, Protein, Ubiquitin