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172
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BMCBI
2010
185views more  BMCBI 2010»
14 years 10 months ago
MetaPIGA v2.0: maximum likelihood large phylogeny estimation using the metapopulation genetic algorithm and other stochastic heu
Background: The development, in the last decade, of stochastic heuristics implemented in robust application softwares has made large phylogeny inference a key step in most compara...
Raphaël Helaers, Michel C. Milinkovitch
BMCBI
2010
216views more  BMCBI 2010»
14 years 10 months ago
Bayesian Inference of the Number of Factors in Gene-Expression Analysis: Application to Human Virus Challenge Studies
Background: Nonparametric Bayesian techniques have been developed recently to extend the sophistication of factor models, allowing one to infer the number of appropriate factors f...
Bo Chen, Minhua Chen, John William Paisley, Aimee ...
155
Voted
BIB
2011
14 years 10 months ago
Mutational analysis in RNAs: comparing programs for RNA deleterious mutation prediction
Programs for RNA mutational analysis that are structure-based and rely on secondary structure prediction have been developed and expanded in the past several years. They can be us...
Danny Barash, Alexander Churkin
151
Voted
BIOINFORMATICS
2011
14 years 10 months ago
Inverse perturbation for optimal intervention in gene regulatory networks
Motivation: Analysis and intervention in the dynamics of gene regulatory networks is at the heart of emerging efforts in the development of modern treatment of numerous ailments i...
Nidhal Bouaynaya, Roman Shterenberg, Dan Schonfeld
152
Voted
BMCBI
2011
14 years 10 months ago
N-gram analysis of 970 microbial organisms reveals presence of biological language models
Background: It has been suggested previously that genome and proteome sequences show characteristics typical of natural-language texts such as “signature-style” word usage ind...
Hatice U. Osmanbeyoglu, Madhavi Ganapathiraju
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