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BMCBI
2010
13 years 7 months ago
2010
Background: Human genome contains millions of common single nucleotide polymorphisms (SNPs) and these SNPs play an important role in understanding the association between genetic ...
BMCBI
2008
13 years 7 months ago
2008
Background: Eukaryotic cell cycle is a complex process and is precisely regulated at many levels. Many genes specific to the cell cycle are regulated transcriptionally and are exp...
BMCBI
2010
13 years 7 months ago
2010
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
BMCBI
2007
13 years 7 months ago
2007
Background: RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdo...
BMCBI
2006
13 years 7 months ago
2006
Background: We recently developed the Paired End diTag (PET) strategy for efficient characterization of mammalian transcriptomes and genomes. The paired end nature of short PET se...