The protein folding problem consists of predicting the functional (native) structure of the protein given its linear sequence of amino acids. Despite extensive progress made in un...
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Efficiency enhancement techniques--such as parallelization and hybridization--are among the most important ingredients of practical applications of genetic and evolutionary algori...
We present in this paper a multilevel floorplanning/placement framework based on the B*-tree representation, called MB*-tree, to handle the floorplanning and packing for large-sca...
— Modern CPUs operate at GHz frequencies, but the latencies of memory accesses are still relatively large, in the order of hundreds of cycles. Deeper cache hierarchies with large...
Konrad Malkowski, Greg M. Link, Padma Raghavan, Ma...