6010 search results - page 21 / 1202 » Computational Approaches to Drug Design |
CIKM
2006
Springer
13 years 11 months ago
2006
Springer
The ability to retrieve molecules based on structural similarity has use in many applications, from disease diagnosis and treatment to drug discovery and design. In this paper, we...
BMCBI
2010
13 years 7 months ago
2010
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
BMCBI
2006
13 years 7 months ago
2006
Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
NAR
2011
12 years 10 months ago
2011
The subcellular localization (SCL) of a microbial protein provides clues about its function, its suitability as a drug, vaccine or diagnostic target and aids experimental design. ...
CSB
2005
IEEE
14 years 1 months ago
2005
IEEE
We have previously developed a method [1] for the inverse design of small ligands. This method can be used to design novel compounds with optimized properties (such as drugs) and ...