Sciweavers

6010 search results - page 97 / 1202
» Computational Approaches to Drug Design
Sort
View
BMCBI
2011
13 years 1 months ago
Conotoxin Protein Classification Using Free Scores of Words and Support Vector Machines
Background: Conotoxin has been proven to be effective in drug design and could be used to treat various disorders such as schizophrenia, neuromuscular disorders and chronic pain. ...
Nazar Zaki, Stefan Wolfsheimer, Grégory Nue...
NAR
2011
233views Computer Vision» more  NAR 2011»
13 years 1 months ago
ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures
ArachnoServer (www.arachnoserver.org) is a manually curated database providing information on the sequence, structure and biological activity of protein toxins from spider venoms....
Volker Herzig, David L. A. Wood, Felicity Newell, ...
BMCBI
2010
105views more  BMCBI 2010»
13 years 10 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
NAR
2011
260views Computer Vision» more  NAR 2011»
13 years 1 months ago
ASD: a comprehensive database of allosteric proteins and modulators
Allostery is the most direct, rapid and efficient way of regulating protein function, ranging from the control of metabolic mechanisms to signaltransduction pathways. However, an ...
Zhimin Huang, Liang Zhu, Yan Cao, Geng Wu, Xinyi L...
DAC
2001
ACM
14 years 11 months ago
Addressing the System-on-a-Chip Interconnect Woes Through Communication-Based Design
Communication-based design represents a formal approach to systemon-a-chip design that considers communication between components as important as the computations they perform. Ou...
Marco Sgroi, Michael Sheets, Andrew Mihal, Kurt Ke...