Background: High-throughput methods identify an overwhelming number of protein-protein interactions. However, the limited accuracy of these methods results in the false identifica...
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Allostery is the most direct, rapid and efficient way of regulating protein function, ranging from the control of metabolic mechanisms to signaltransduction pathways. However, an ...
Zhimin Huang, Liang Zhu, Yan Cao, Geng Wu, Xinyi L...
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...