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BMCBI
2011
13 years 2 months ago
Worm Phenotype Ontology: integrating phenotype data within and beyond the C. elegans community
Background: Caenorhabditis elegans gene-based phenotype information dates back to the 1970’s, beginning with Sydney Brenner and the characterization of behavioral and morphologi...
Gary Schindelman, Jolene Fernandes, Carol Bastiani...
BMCBI
2011
13 years 2 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
MMAS
2011
Springer
13 years 2 months ago
Scalable Bayesian Reduced-Order Models for Simulating High-Dimensional Multiscale Dynamical Systems
While existing mathematical descriptions can accurately account for phenomena at microscopic scales (e.g. molecular dynamics), these are often high-dimensional, stochastic and thei...
Phaedon-Stelios Koutsourelakis, Elias Bilionis
SIAMSC
2011
151views more  SIAMSC 2011»
13 years 2 months ago
Inexact Newton Methods with Restricted Additive Schwarz Based Nonlinear Elimination for Problems with High Local Nonlinearity
The classical inexact Newton algorithm is an efficient and popular technique for solving large sparse nonlinear system of equations. When the nonlinearities in the system are wellb...
Xiao-Chuan Cai, Xuefeng Li
NAR
2010
129views more  NAR 2010»
13 years 2 months ago
PROSESS: a protein structure evaluation suite and server
PROSESS (PROtein Structure Evaluation Suite and Server) is a web server designed to evaluate and validate protein structures generated by X-ray crystallography, NMR spectroscopy o...
Mark V. Berjanskii, Yongjie Liang, Jianjun Zhou, P...
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