PROSESS: a protein structure evaluation suite and server

PROSESS (PROtein Structure Evaluation Suite and Server) is a web server designed to evaluate and validate protein structures generated by X-ray crystallography, NMR spectroscopy or computational modeling. While many structure evaluation packages have been developed over the past 20 years, PROSESS is unique in its comprehensiveness, its capacity to evaluate X-ray, NMR and predicted structures as well as its ability to evaluate a variety of experimental NMR data. PROSESS integrates a variety of previously developed, well-known and thoroughly tested methods to evaluate both global and residue specific: (i) covalent and geometric quality; (ii) non-bonded/packing quality; (iii) torsion angle quality; (iv) chemical shift quality and (v) NOE quality. In particular, PROSESS uses VADAR for coordinate, packing, H-bond, secondary structure and geometric analysis, GeNMR for calculating folding, threading and solvent energetics, ShiftX for calculating chemical shift correlations, RCI for correlati...

• Type: Journal
• Year: 2010
• Where: NAR
• Authors: Mark V. Berjanskii, Yongjie Liang, Jianjun Zhou, Peter Tang, Paul Stothard, You Zhou, Joseph A. Cruz, Cam Macdonell, Guohui Lin, Paul Lu, David S. Wishart
• Keywords: Evaluate, NAR 2010, Protein Structures, Structure Evaluation