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» Constraint Based Methods for Biological Sequence Analysis
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119
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CBMS
2005
IEEE
15 years 9 months ago
An Ontology-Driven Clustering Method for Supporting Gene Expression Analysis
The Gene Ontology (GO) is an important knowledge resource for biologists and bioinformaticians. This paper explores the integration of similarity information derived from GO into ...
Haiying Wang, Francisco Azuaje, Olivier Bodenreide...
RECOMB
2005
Springer
16 years 3 months ago
Combinatorial Genetic Regulatory Network Analysis Tools for High Throughput Transcriptomic Data
: A series of genome-scale algorithms and high-performance implementations is described and shown to be useful in the genetic analysis of gene transcription. With them it is possib...
Elissa J. Chesler, Michael A. Langston
143
Voted
BMCBI
2007
149views more  BMCBI 2007»
15 years 3 months ago
SAMPI: Protein Identification with Mass Spectra Alignments
Background: Mass spectrometry based peptide mass fingerprints (PMFs) offer a fast, efficient, and robust method for protein identification. A protein is digested (usually by tryps...
Hans-Michael Kaltenbach, Andreas Wilke, Sebastian ...
136
Voted
RECOMB
2006
Springer
16 years 3 months ago
New Methods for Detecting Lineage-Specific Selection
Abstract. So far, most methods for identifying sequences under selection based on comparative sequence data have either assumed selectional pressures are the same across all branch...
Adam C. Siepel, Katherine S. Pollard, David Haussl...
GECCO
2008
Springer
135views Optimization» more  GECCO 2008»
15 years 4 months ago
Evolving sequence patterns for prediction of sub-cellular locations of eukaryotic proteins
A genetic algorithm (GA) is utilised to discover known and novel PROSITE-like sequence templates that can be used to classify the sub-cellular location of eukaryotic proteins. Whi...
Greg Paperin