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BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 7 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
BMCBI
2006
136views more  BMCBI 2006»
13 years 7 months ago
Metric for Measuring the Effectiveness of Clustering of DNA Microarray Expression
Background: The recent advancement of microarray technology with lower noise and better affordability makes it possible to determine expression of several thousand genes simultane...
Raja Loganantharaj, Satish Cheepala, John Clifford
BMCBI
2007
148views more  BMCBI 2007»
13 years 7 months ago
p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data
Background: The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlapping functions in pivotal cellular processes such as DNA synthesis a...
Elisabetta Sbisà, Domenico Catalano, Giorgi...
RECOMB
2008
Springer
14 years 8 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir
BMCBI
2007
139views more  BMCBI 2007»
13 years 7 months ago
Significance analysis of microarray transcript levels in time series experiments
Background: Microarray time series studies are essential to understand the dynamics of molecular events. In order to limit the analysis to those genes that change expression over ...
Barbara Di Camillo, Gianna Toffolo, Sreekumaran K....