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IDA
2007
Springer
13 years 7 months ago
An unsupervised clustering approach for leukaemia classification based on DNA micro-arrays data
: DNA micro-arrays provide thousands of genomic expressions on the same subject. A main issue is then to find the subset of genes whose degeneration is responsible of a certain typ...
Simone Garatti, Sergio Bittanti, Diego Liberati, A...
ICASSP
2010
IEEE
13 years 8 months ago
Structuring a gene network using a multiresolution independence test
In order to structure a gene network, a score-based approach is often used. A score-based approach, however, is problematic because by assuming a probability distribution, one is ...
Takayuki Yamamoto, Tetsuya Takiguchi, Yasuo Ariki
BMCBI
2007
143views more  BMCBI 2007»
13 years 8 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
BMCBI
2010
131views more  BMCBI 2010»
13 years 8 months ago
Prediction of epigenetically regulated genes in breast cancer cell lines
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
GOAL: A software tool for assessing biological significance of genes groups
Background: Modern high throughput experimental techniques such as DNA microarrays often result in large lists of genes. Computational biology tools such as clustering are then us...
Alain B. Tchagang, Alexander Gawronski, Hugo B&eac...