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BMCBI
2007
139views more  BMCBI 2007»
13 years 8 months ago
Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
Background: RNA interference (RNAi) is a naturally occurring phenomenon that results in the suppression of a target RNA sequence utilizing a variety of possible methods and pathwa...
Andrew S. Peek
BMCBI
2010
108views more  BMCBI 2010»
13 years 8 months ago
Predicting changes in protein thermostability brought about by single- or multi-site mutations
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
Jian Tian, Ningfeng Wu, Xiaoyu Chu, Yunliu Fan
BMCBI
2010
133views more  BMCBI 2010»
13 years 8 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
CGF
2008
141views more  CGF 2008»
13 years 8 months ago
Interactive Visualization of Multimodal Volume Data for Neurosurgical Tumor Treatment
Teaser Figure: Left: Brain, visualized using silhouettes, the lesion's spatial depth is displayed using a ring. Center: Combined rendering of brain tissue, skull and fiber tr...
Christian Rieder, Felix Ritter, Matthias Raspe, He...
BMCBI
2006
169views more  BMCBI 2006»
13 years 8 months ago
Comparative analysis of haplotype association mapping algorithms
Background: Finding the genetic causes of quantitative traits is a complex and difficult task. Classical methods for mapping quantitative trail loci (QTL) in miceuse an F2 cross b...
Phillip McClurg, Mathew T. Pletcher, Tim Wiltshire...