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» Current approaches to gene regulatory network modelling
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BMCBI
2010
172views more  BMCBI 2010»
13 years 6 months ago
Inferring gene regression networks with model trees
Background: Novel strategies are required in order to handle the huge amount of data produced by microarray technologies. To infer gene regulatory networks, the first step is to f...
Isabel A. Nepomuceno-Chamorro, Jesús S. Agu...
EVOW
2007
Springer
14 years 26 days ago
Modeling the Shoot Apical Meristem in A. thaliana : Parameter Estimation for Spatial Pattern Formation
Understanding the self-regulatory mechanisms controlling the spatial and temporal structure of multicellular organisms represents one of the major challenges in molecular biology. ...
Tim Hohm, Eckart Zitzler
IJKDB
2010
141views more  IJKDB 2010»
13 years 4 months ago
Mining Frequent Boolean Expressions: Application to Gene Expression and Regulatory Modeling
Regulatory network analysis and other bioinformatics tasks require the ability to induce and represent arbitrary boolean expressions from data sources. We introduce a novel framew...
Mohammed Javeed Zaki, Naren Ramakrishnan, Lizhuang...
BMCBI
2010
97views more  BMCBI 2010»
13 years 1 months ago
A semi-parametric Bayesian model for unsupervised differential co-expression analysis
Background: Differential co-expression analysis is an emerging strategy for characterizing disease related dysregulation of gene expression regulatory networks. Given pre-defined ...
Johannes M. Freudenberg, Siva Sivaganesan, Michael...
BMCBI
2008
114views more  BMCBI 2008»
13 years 6 months ago
The pairwise disconnectivity index as a new metric for the topological analysis of regulatory networks
Background: Currently, there is a gap between purely theoretical studies of the topology of large bioregulatory networks and the practical traditions and interests of experimental...
Anatolij Potapov, Björn Goemann, Edgar Wingen...