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» Current approaches to gene regulatory network modelling
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MIE
2008
116views Healthcare» more  MIE 2008»
13 years 9 months ago
Gene Regulation Ontology (GRO): Design Principles and Use Cases
The Gene Regulation Ontology (GRO) is designed as a novel approach to model complex events that are part of the gene regulatory processes. We introduce the design requirements for ...
Elena Beisswanger, Vivian Lee, Jung-jae Kim, Dietr...
CGF
2008
142views more  CGF 2008»
13 years 8 months ago
Visualizing Genome Expression and Regulatory Network Dynamics in Genomic and Metabolic Context
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...
Michel A. Westenberg, Sacha A. F. T. van Hijum, Os...
NAR
2011
221views Computer Vision» more  NAR 2011»
12 years 11 months ago
AGRIS: the Arabidopsis Gene Regulatory Information Server, an update
The Arabidopsis Gene Regulatory Information Server (AGRIS; http://arabidopsis.med.ohio-state .edu/) provides a comprehensive resource for gene regulatory studies in the model plan...
Alper Yilmaz, Maria Katherine Mejia-Guerra, Kyle K...
BMCBI
2007
168views more  BMCBI 2007»
13 years 8 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
ALIFE
2005
13 years 8 months ago
A Gene Network Model for Developing Cell Lineages
Biological development is a remarkably complex process. A single cell, in an appropriate environment, contains sufficient information to generate a variety of differentiated cell ...
Nicholas Geard, Janet Wiles