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» Current approaches to gene regulatory network modelling
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HISB
2011
99views more  HISB 2011»
12 years 8 months ago
Quantitative Modeling the Saccharomyces cerevisiae FLR1 Regulatory Network Using an S-System Formalism
—We address the problem of finding a mathematical model for the genetic network regulating the stress response of the yeast Saccharomyces cerevisiae to the fungicide mancozeb. A...
Dulce Calçada, Susana Vinga, Ana T. Freitas...
BMCBI
2007
103views more  BMCBI 2007»
13 years 8 months ago
Dynamic simulation of regulatory networks using SQUAD
Background: The ambition of most molecular biologists is the understanding of the intricate network of molecular interactions that control biological systems. As scientists uncove...
Alessandro Di Cara, Abhishek Garg, Giovanni De Mic...
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
14 years 2 months ago
iSimBioSys: An "In Silico" Discrete Event Simulation Framework for Modeling Biological Systems
The genome projects have provided comprehensive information about the basic building blocks of life. The next challenge is to understand how biological functions emerge from compl...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
BMCBI
2008
129views more  BMCBI 2008»
13 years 8 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
ICCAD
2005
IEEE
81views Hardware» more  ICCAD 2005»
14 years 5 months ago
Kauffman networks: analysis and applications
Abstract— A Kauffman network is an abstract model of gene regulatory networks. Each gene is represented by a vertex. An edge from one vertex to another implies that the former ge...
Elena Dubrova, Maxim Teslenko, Andrés Marti...