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CANDC
2007
ACM
13 years 8 months ago
Chromosome segregation in Escherichia coli division: A free energy-driven string model
Although the mechanisms of eukaryotic chromosome segregation and cell division have been elucidated to a certain extent, those for bacteria remain largely unknown. Here we present...
Jianmiao Fan, Kagan Tuncay, Peter J. Ortoleva
NAR
2006
59views more  NAR 2006»
13 years 8 months ago
GenDecoder: genetic code prediction for metazoan mitochondria
Although the majority of the organisms use the same genetic code to translate DNA, several variants have been described in a wide range of organisms, both in nuclear and organella...
Federico Abascal, Rafael Zardoya, David Posada
TCBB
2008
122views more  TCBB 2008»
13 years 7 months ago
Mixed Integer Linear Programming for Maximum-Parsimony Phylogeny Inference
Reconstruction of phylogenetic trees is a fundamental problem in computational biology. While excellent heuristic methods are available for many variants of this problem, new adva...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...
BMCBI
2007
166views more  BMCBI 2007»
13 years 8 months ago
Data handling strategies for high throughput pyrosequencers
Background: New high throughput pyrosequencers such as the 454 Life Sciences GS 20 are capable of massively parallelizing DNA sequencing providing an unprecedented rate of output ...
Gabriele A. Trombetti, Raoul J. P. Bonnal, Ermanno...
RECOMB
2005
Springer
14 years 8 months ago
Improved Recombination Lower Bounds for Haplotype Data
Recombination is an important evolutionary mechanism responsible for the genetic diversity in humans and other organisms. Recently, there has been extensive research on understandi...
Vineet Bafna, Vikas Bansal