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» DNA Computing in Microreactors
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BMCBI
2004
207views more  BMCBI 2004»
13 years 8 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...
BMCBI
2008
104views more  BMCBI 2008»
13 years 8 months ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
BMCBI
2006
145views more  BMCBI 2006»
13 years 8 months ago
Fast-Find: A novel computational approach to analyzing combinatorial motifs
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
Micah Hamady, Erin Peden, Rob Knight, Ravinder Sin...
RECOMB
2007
Springer
14 years 8 months ago
GIMscan: A New Statistical Method for Analyzing Whole-Genome Array CGH Data
Genetic instability represents an important type of biological markers for cancer and many other diseases. Array Comparative Genome Hybridization (aCGH) is a high-throughput cytoge...
Yanxin Shi, Fan Guo, Wei Wu, Eric P. Xing
RECONFIG
2009
IEEE
182views VLSI» more  RECONFIG 2009»
14 years 2 months ago
Scalability Studies of the BLASTn Scan and Ungapped Extension Functions
BLASTn is a ubiquitous tool used for large scale DNA analysis. Detailed profiling tests reveal that the most computationally intensive sections of the BLASTn algorithm are the sc...
Siddhartha Datta, Ron Sass