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ICPR
2004
IEEE
14 years 10 months ago
Missing Microarray Data Estimation Based on Projection onto Convex Sets Method
DNA microarrays have gained widespread uses in biological studies. Missing values in a microarray experiment must be estimated before further analysis. In this paper, we propose a...
Alan Wee-Chung Liew, Hong Yan, Xiangchao Gan
RECOMB
2009
Springer
14 years 9 months ago
Finding Biologically Accurate Clusterings in Hierarchical Tree Decompositions Using the Variation of Information
Abstract. Hierarchical clustering is a popular method for grouping together similar elements based on a distance measure between them. In many cases, annotation information for som...
Saket Navlakha, James Robert White, Niranjan Nagar...
RECOMB
2008
Springer
14 years 9 months ago
Duplication Mechanism and Disruptions in Flanking Regions Influence the Fate of Mammalian Gene Duplicates
Here we identify duplicated genes in five mammalian genomes and classify these duplicates based on the mechanisms by which they were generated. Retrotransposition accounts for at l...
Paul Ryvkin, Jin Jun, Edward Hemphill, Craig Nelso...
BMEI
2008
IEEE
14 years 3 months ago
A New Approach for Tree Alignment Based on Local Re-Optimization
Multiple sequence alignment is the most fundamental task in bioinformatics and computational biology. In this paper, we present a new algorithm to conduct multiple sequences align...
Feng Yue, Jijun Tang
DAC
2006
ACM
14 years 3 months ago
Automated design of pin-constrained digital microfluidic arrays for lab-on-a-chip applications*
Microfluidics-based biochips, also referred to as lab-on-a-chip (LoC), are devices that integrate fluid-handling functions such as sample preparation, analysis, separation, and de...
William L. Hwang, Fei Su, Krishnendu Chakrabarty