DNA microarrays have gained widespread uses in biological studies. Missing values in a microarray experiment must be estimated before further analysis. In this paper, we propose a...
Abstract. Hierarchical clustering is a popular method for grouping together similar elements based on a distance measure between them. In many cases, annotation information for som...
Saket Navlakha, James Robert White, Niranjan Nagar...
Here we identify duplicated genes in five mammalian genomes and classify these duplicates based on the mechanisms by which they were generated. Retrotransposition accounts for at l...
Paul Ryvkin, Jin Jun, Edward Hemphill, Craig Nelso...
Multiple sequence alignment is the most fundamental task in bioinformatics and computational biology. In this paper, we present a new algorithm to conduct multiple sequences align...
Microfluidics-based biochips, also referred to as lab-on-a-chip (LoC), are devices that integrate fluid-handling functions such as sample preparation, analysis, separation, and de...