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BMCBI
2007
109views more  BMCBI 2007»
13 years 7 months ago
TABASCO: A single molecule, base-pair resolved gene expression simulator
Background: Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavio...
Sriram Kosuri, Jason R. Kelly, Drew Endy
RECOMB
2009
Springer
14 years 8 months ago
How Many Bootstrap Replicates Are Necessary?
Phylogenetic Bootstrapping (BS) is a standard technique for inferring confidence values on phylogenetic trees that is based on reconstructing many trees from minor variations of th...
Nicholas D. Pattengale, Masoud Alipour, Olaf R. P....
BMCBI
2007
197views more  BMCBI 2007»
13 years 7 months ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park
BMCBI
2007
164views more  BMCBI 2007»
13 years 7 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...
BMCBI
2007
111views more  BMCBI 2007»
13 years 7 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda