Sciweavers

621 search results - page 30 / 125
» DNA Computing
Sort
View
RECOMB
2002
Springer
14 years 10 months ago
Deconvolving sequence variation in mixed DNA populations
We present an original approach to identifying sequence variants in a mixed DNA population from sequence trace data. The heart of the method is based on parsimony: given a wildtyp...
Andy Wildenberg, Steven Skiena, Pavel Sumazin
IPPS
2003
IEEE
14 years 3 months ago
Accurate Method for Fast Design of Diagnostic Oligonucleotide Probe Sets for DNA Microarrays
We present a method for the automatic generation of oligonucleotide probe sets for DNA microarrays. This approach is well suited particularly for specificity evaluation of design...
Andreas Krause, Markus Kräutner, Harald Meier
RECOMB
2007
Springer
14 years 10 months ago
A Feature-Based Approach to Modeling Protein-DNA Interactions
Transcription factor (TF) binding to its DNA target site is a fundamental regulatory interaction. The most common model used to represent TF binding specificities is a position spe...
Eilon Sharon, Eran Segal
BMCBI
2006
86views more  BMCBI 2006»
13 years 10 months ago
MCALIGN2: Faster, accurate global pairwise alignment of non-coding DNA sequences based on explicit models of indel evolution
Background: Non-coding DNA sequences comprise a very large proportion of the total genomic content of mammals, most other vertebrates, many invertebrates, and most plants. Unravel...
Jun Wang, Peter D. Keightley, Toby Johnson
RECOMB
2002
Springer
14 years 10 months ago
DNA sequence evolution with neighbor-dependent mutation
We introduce a model of DNA sequence evolution which can account for biases in mutation rates that depend on the identity of the neighboring bases. An analytic solution for this c...
Peter F. Arndt, Christopher B. Burge, Terence Hwa