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RECOMB
1997
Springer
14 years 2 months ago
Sequence alignment with tandem duplication
Algorithm development for comparing and aligning biological sequences has, until recently, been based on the SI model of mutational events which assumes that modi cation of sequen...
Gary Benson
SBACPAD
2003
IEEE
120views Hardware» more  SBACPAD 2003»
14 years 3 months ago
Comparison of Genomes Using High-Performance Parallel Computing
Comparison of the DNA sequences and genes of two genomes can be useful to investigate the common functionalities of the corresponding organisms and get a better understanding of h...
Nalvo F. Almeida Jr., Carlos E. R. Alves, Edson C&...
BMCBI
2008
102views more  BMCBI 2008»
13 years 10 months ago
Stability of the core domain of p53: insights from computer simulations
: The tumour suppressor protein p53 protein has a core domain that binds DNA and is the site for most oncogenic mutations. This domain is quite unstable compared to its homologs p...
Arumugam Madhumalar, Derek John Smith, Chandra Ver...
BMCBI
2005
246views more  BMCBI 2005»
13 years 10 months ago
ParPEST: a pipeline for EST data analysis based on parallel computing
Background: Expressed Sequence Tags (ESTs) are short and error-prone DNA sequences generated from the 5' and 3' ends of randomly selected cDNA clones. They provide an im...
Nunzio D'Agostino, Mario Aversano, Maria Luisa Chi...
BMCBI
2006
152views more  BMCBI 2006»
13 years 10 months ago
Amplification of the Gene Ontology annotation of Affymetrix probe sets
Background: The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete a...
Enrique M. Muro, Carolina Perez-Iratxeta, Miguel A...