Optical mapping is an integrated system for the analysis of single DNA molecules. It constructs restriction maps (noted as “optical map”) from individual DNA molecules present...
Haifeng Li, Anton Valouev, David C. Schwartz, Mich...
— DNA sequence basecalling is commonly regarded as a solved problem, despite significant error rates being reflected in inaccuracies in databases and genome annotations. These er...
In many applications string pattern matching is one of the most intensive tasks in terms of computation time and memory accesses. Network Intrusion Detection Systems and DNA Seque...
Ivano Bonesana, Marco Paolieri, Marco D. Santambro...
Background: gene identification in genomic DNA sequences by computational methods has become an important task in bioinformatics and computational gene prediction tools are now es...
Performance of DNA sequencing-by-synthesis systems is fundamentally limited by the stochastic nature of the underlying biochemical process. We develop a novel graphical representa...