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» DNA binding sites: representation and discovery
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BMCBI
2007
141views more  BMCBI 2007»
13 years 6 months ago
HeliCis: a DNA motif discovery tool for colocalized motif pairs with periodic spacing
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...
Erik Larsson, Per Lindahl, Petter Mostad
APBC
2008
231views Bioinformatics» more  APBC 2008»
13 years 8 months ago
Optimal Algorithm for Finding DNA Motifs with Nucleotide Adjacent Dependency
: Finding motifs and the corresponding binding sites is a critical and challenging problem in studying the process of gene expression. String and matrix representations are two pop...
Francis Y. L. Chin, Henry C. M. Leung, Man-Hung Si...
BMCBI
2010
152views more  BMCBI 2010»
13 years 6 months ago
FITBAR: a web tool for the robust prediction of prokaryotic regulons
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
Jacques Oberto
BMCBI
2006
87views more  BMCBI 2006»
13 years 6 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
RECOMB
2007
Springer
14 years 24 days ago
Nucleosome Occupancy Information Improves de novo Motif Discovery
A complete understanding of transcriptional regulatory processes in the cell requires identification of transcription factor binding sites on a genomewide scale. Unfortunately, th...
Leelavati Narlikar, Raluca Gordân, Alexander...