Interactions that determinecellular fate are exceedingly complex, can take place at different levels of gene regulation and involve a large numberof components(such as genes, prot...
Agent-based simulations are an increasingly popular means of exploring and understanding complex social systems. In order to be useful, these simulations must capture a range of a...
David Scerri, Alexis Drogoul, Sarah L. Hickmott, L...
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
Background: Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, un...
Chilamakuri C. S. Reddy, Khader Shameer, Bernard O...