Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
Background: BLAST searches are widely used for sequence alignment. The search results are commonly adopted for various functional and comparative genomics tasks such as annotating...
Background: The Gene Ontology has become an extremely useful tool for the analysis of genomic data and structuring of biological knowledge. Several excellent software tools for na...
Rachel S. G. Sealfon, Matthew A. Hibbs, Curtis Hut...
The recent explosion in protein data generated from both directed small-scale studies and largescale proteomics efforts has greatly expanded the quantity of available protein info...
Robert S. Nash, Shuai Weng, Benjamin C. Hitz, Rama...
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...