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BMCBI
2010
112views more  BMCBI 2010»
13 years 6 months ago
In silico fragmentation for computer assisted identification of metabolite mass spectra
Background: Mass spectrometry has become the analytical method of choice in metabolomics research. The identification of unknown compounds is the main bottleneck. In addition to t...
Sebastian Wolf, Stephan Schmidt, Matthias Mül...
BMCBI
2008
106views more  BMCBI 2008»
13 years 6 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
BMCBI
2007
146views more  BMCBI 2007»
13 years 6 months ago
PubMed related articles: a probabilistic topic-based model for content similarity
Background: We present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document ...
Jimmy J. Lin, W. John Wilbur
BMCBI
2006
124views more  BMCBI 2006»
13 years 6 months ago
HybGFS: a hybrid method for genome-fingerprint scanning
Background: Protein identification based on mass spectrometry (MS) has previously been performed using peptide mass fingerprinting (PMF) or tandem MS (MS/MS) database searching. H...
Kosaku Shinoda, Nozomu Yachie, Takeshi Masuda, Nao...
JIB
2007
124views more  JIB 2007»
13 years 6 months ago
Analysis of integrated biomolecular networks using a generic network analysis suite
The informative value of biomolecular networks has shifted from being solely information resources for possible cellular partners (whether these embody proteins, (ribo)nucleic aci...
Matthias Oesterheld, Hans-Werner Mewes, Volker St&...