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BMCBI
2005
141views more  BMCBI 2005»
13 years 8 months ago
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
TKDE
2008
127views more  TKDE 2008»
13 years 8 months ago
Maximal Subspace Coregulated Gene Clustering
Clustering is a popular technique for analyzing microarray data sets, with n genes and m experimental conditions. As explored by biologists, there is a real need to identify coregu...
Yuhai Zhao, Jeffrey Xu Yu, Guoren Wang, Lei Chen 0...
BMCBI
2005
107views more  BMCBI 2005»
13 years 8 months ago
ProbeMaker: an extensible framework for design of sets of oligonucleotide probes
Background: Procedures for genetic analyses based on oligonucleotide probes are powerful tools that can allow highly parallel investigations of genetic material. Such procedures r...
Johan Stenberg, Mats Nilsson, Ulf Landegren
BMCBI
2005
107views more  BMCBI 2005»
13 years 8 months ago
Protein subcellular localization prediction for Gram-negative bacteria using amino acid subalphabets and a combination of multip
Background: Predicting the subcellular localization of proteins is important for determining the function of proteins. Previous works focused on predicting protein localization in...
Jiren Wang, Wing-Kin Sung, Arun Krishnan, Kuo-Bin ...
BMCBI
2005
157views more  BMCBI 2005»
13 years 8 months ago
Decision Forest Analysis of 61 Single Nucleotide Polymorphisms in a Case-Control Study of Esophageal Cancer; a novel method
Background: Systematic evaluation and study of single nucleotide polymorphisms (SNPs) made possible by high throughput genotyping technologies and bioinformatics promises to provi...
Qian Xie, Luke D. Ratnasinghe, Huixiao Hong, Roger...
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