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BMCBI
2008
114views more  BMCBI 2008»
15 years 4 months ago
TiGER: A database for tissue-specific gene expression and regulation
Background: Understanding how genes are expressed and regulated in different tissues is a fundamental and challenging question. However, most of currently available biological dat...
Xiong Liu, Xueping Yu, Donald J. Zack, Heng Zhu, J...
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BMCBI
2010
146views more  BMCBI 2010»
15 years 4 months ago
Nonnegative principal component analysis for mass spectral serum profiles and biomarker discovery
Background: As a novel cancer diagnostic paradigm, mass spectroscopic serum proteomic pattern diagnostics was reported superior to the conventional serologic cancer biomarkers. Ho...
Henry Han
BMCBI
2008
118views more  BMCBI 2008»
15 years 4 months ago
MetWAMer: eukaryotic translation initiation site prediction
Background: Translation initiation site (TIS) identification is an important aspect of the gene annotation process, requisite for the accurate delineation of protein sequences fro...
Michael E. Sparks, Volker Brendel
BMCBI
2010
108views more  BMCBI 2010»
15 years 4 months ago
A genetic ensemble approach for gene-gene interaction identification
Background: It has now become clear that gene-gene interactions and gene-environment interactions are ubiquitous and fundamental mechanisms for the development of complex diseases...
Pengyi Yang, Joshua W. K. Ho, Albert Y. Zomaya, Bi...
BMCBI
2007
182views more  BMCBI 2007»
15 years 4 months ago
Hybrid elementary flux analysis/nonparametric modeling: application for bioprocess control
Background: The progress in the "-omic" sciences has allowed a deeper knowledge on many biological systems with industrial interest. This knowledge is still rarely used ...
Ana P. Teixeira, Carlos Alves, Paula M. Alves, Man...