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NAR
2011
305views Computer Vision» more  NAR 2011»
12 years 11 months ago
CDD: a Conserved Domain Database for the functional annotation of proteins
NCBI’s Conserved Domain Database (CDD) is a resource for the annotation of protein sequences with the location of conserved domain footprints, and functional sites inferred from...
Aron Marchler-Bauer, Shennan Lu, John B. Anderson,...
BMCBI
2006
145views more  BMCBI 2006»
13 years 8 months ago
Querying the public databases for sequences using complex keywords contained in the feature lines
Background: High throughput technologies often require the retrieval of large data sets of sequences. Retrieval of EMBL or GenBank entries using keywords is easy using tools such ...
Olivier Croce, Michaël Lamarre, Richard Chris...
BMCBI
2008
142views more  BMCBI 2008»
13 years 8 months ago
Optimal neighborhood indexing for protein similarity search
Background: Similarity inference, one of the main bioinformatics tasks, has to face an exponential growth of the biological data. A classical approach used to cope with this data ...
Pierre Peterlongo, Laurent Noé, Dominique L...
BMCBI
2006
145views more  BMCBI 2006»
13 years 8 months ago
Fast-Find: A novel computational approach to analyzing combinatorial motifs
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
Micah Hamady, Erin Peden, Rob Knight, Ravinder Sin...
BMCBI
2008
144views more  BMCBI 2008»
13 years 8 months ago
Rule-based knowledge aggregation for large-scale protein sequence analysis of influenza A viruses
Background: The explosive growth of biological data provides opportunities for new statistical and comparative analyses of large information sets, such as alignments comprising te...
Olivo Miotto, Tin Wee Tan, Vladimir Brusic