Sciweavers

88 search results - page 5 / 18
» Decomposing Gene Expression into Cellular Processes
Sort
View
BMCBI
2008
145views more  BMCBI 2008»
13 years 10 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
ICCS
2003
Springer
14 years 3 months ago
Modelling Developmental Regulatory Networks
Abstract. This paper introduces a model for simulating regulatory networks that is capable of reproducing spatial and temporal expression patterns in developmental processes. The m...
Tommy Krul, Jaap A. Kaandorp, Joke G. Blom
SDM
2008
SIAM
157views Data Mining» more  SDM 2008»
13 years 11 months ago
ROC-tree: A Novel Decision Tree Induction Algorithm Based on Receiver Operating Characteristics to Classify Gene Expression Data
Gene expression information from microarray experiments is a primary form of data for biological analysis and can offer insights into disease processes and cellular behaviour. Suc...
M. Maruf Hossain, Md. Rafiul Hassan, James Bailey
BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation
Background: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gen...
Andreas Kowarsch, Florian Blöchl, Sebastian B...
BMCBI
2011
13 years 1 months ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...