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BMCBI
2008
102views more  BMCBI 2008»
13 years 7 months ago
Stability of the core domain of p53: insights from computer simulations
: The tumour suppressor protein p53 protein has a core domain that binds DNA and is the site for most oncogenic mutations. This domain is quite unstable compared to its homologs p...
Arumugam Madhumalar, Derek John Smith, Chandra Ver...
BMCBI
2007
94views more  BMCBI 2007»
13 years 7 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
LOBJET
2006
127views more  LOBJET 2006»
13 years 7 months ago
A Definition, Overview and Taxonomy of Generic Aspect Languages
ABSTRACT. Aspect-orientation promises better modularity than pure object-oriented decomposition. A typical benefit of increased modularity is ease of maintenance, evolution and reu...
Günter Kniesel, Tobias Rho
CN
2004
130views more  CN 2004»
13 years 7 months ago
The effect of bandwidth and buffer pricing on resource allocation and QoS
Congestion-based pricing of network resources is a common approach in evolving network architectures that support Quality of Service (QoS). Resource usage and QoS will thus fluctu...
Nan Jin, Scott Jordan
PADS
2003
ACM
14 years 1 months ago
HLA-based Adaptive Distributed Simulation of Wireless Mobile Systems
Wireless networks’ models differ from wired ones at least in the innovative dynamic effects of host-mobility and open-broadcast nature of the wireless medium. Topology changes d...
Luciano Bononi, Gabriele D'Angelo, Lorenzo Donatie...