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» Design of DNA origami
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CORR
2010
Springer
133views Education» more  CORR 2010»
13 years 6 months ago
Scalable, Time-Responsive, Digital, Energy-Efficient Molecular Circuits using DNA Strand Displacement
We propose a novel theoretical biomolecular design to implement any Boolean circuit using the mechanism of DNA strand displacement. The design is scalable: all species of DNA stra...
Ehsan Chiniforooshan, David Doty, Lila Kari, Shinn...
DNA
2001
Springer
139views Bioinformatics» more  DNA 2001»
13 years 11 months ago
DNA Computing in Microreactors
Abstract. The goal of this research is to improve the programmability of DNA-based computers. Novel clockable microreactors can be connected in various ways to solve combinatorial ...
Danny van Noort, Frank-Ulrich Gast, John S. McCask...
BMCBI
2004
154views more  BMCBI 2004»
13 years 6 months ago
Accuracy of cDNA microarray methods to detect small gene expression changes induced by neuregulin on breast epithelial cells
Background: cDNA microarrays are a powerful means to screen for biologically relevant gene expression changes, but are often limited by their ability to detect small changes accur...
Bin Yao, Sanjay N. Rakhade, Qunfang Li, Sharlin Ah...
BMCBI
2006
137views more  BMCBI 2006»
13 years 6 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
BMCBI
2006
91views more  BMCBI 2006»
13 years 6 months ago
Cheminformatics methods for novel nanopore analysis of HIV DNA termini
Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
Stephen Winters-Hilt, Matthew Landry, Mark Akeson,...