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BMCBI
2007
94views more  BMCBI 2007»
13 years 8 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
NC
2008
122views Neural Networks» more  NC 2008»
13 years 8 months ago
Computation with finite stochastic chemical reaction networks
A highly desired part of the synthetic biology toolbox is an embedded chemical microcontroller, capable of autonomously following a logic program specified by a set of instructions...
David Soloveichik, Matthew Cook, Erik Winfree, Jeh...
GPEM
2007
113views more  GPEM 2007»
13 years 8 months ago
An evolutionary approach to cancer chemotherapy scheduling
In this paper, we investigate the employment of evolutionary algorithms as a search mechanism in a decision support system for designing chemotherapy schedules. Chemotherapy invol...
Gabriela Ochoa, Minaya Villasana, Edmund K. Burke
SIGMETRICS
2008
ACM
150views Hardware» more  SIGMETRICS 2008»
13 years 8 months ago
Performance of random medium access control, an asymptotic approach
Random Medium-Access-Control (MAC) algorithms have played an increasingly important role in the development of wired and wireless Local Area Networks (LANs) and yet the performanc...
Charles Bordenave, David McDonald, Alexandre Prout...
BMCBI
2005
118views more  BMCBI 2005»
13 years 8 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
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