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BMCBI
2010
132views more  BMCBI 2010»
13 years 7 months ago
Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Andrés F. Flórez, Daeui Park, Jong B...
BMCBI
2007
111views more  BMCBI 2007»
13 years 7 months ago
Modular co-evolution of metabolic networks
Background: The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known f...
Jing Zhao, Guohui Ding, Lin Tao, Hong Yu, Zhong-Ha...
JDCTA
2010
130views more  JDCTA 2010»
13 years 2 months ago
A Search Algorithm for Clusters in a Network or Graph
A novel breadth-first based structural clustering method for graphs is proposed. Clustering is an important task for analyzing complex networks such as biological networks, World ...
Dongming Chen, Jing Wang, Xiaodong Chen, Xiaowei X...
BICOB
2009
Springer
14 years 2 months ago
Graph Spectral Approach for Identifying Protein Domains
Here we present a simple method based on graph spectral properties to automatically partition multi-domain proteins into individual domains. The identification of structural domain...
Hari Krishna Yalamanchili, Nita Parekh
KDD
2004
ACM
126views Data Mining» more  KDD 2004»
14 years 7 months ago
High-throughput Protein Interactome Data: Minable or Not?
There is an emerging trend in post-genome biology to study the collection of thousands of protein interaction pairs (protein interactome) derived from high-throughput experiments....
Jake Yue Chen, Andrey Y. Sivachenko, Lang Li