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» Determining gene expression on a single pair of microarrays
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BMCBI
2004
180views more  BMCBI 2004»
13 years 7 months ago
Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovaria
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
Virginie M. Aris, Michael J. Cody, Jeff Cheng, Jam...
BMCBI
2010
110views more  BMCBI 2010»
13 years 7 months ago
TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach
Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using mi...
Pietro Zoppoli, Sandro Morganella, Michele Ceccare...
BMCBI
2010
115views more  BMCBI 2010»
13 years 7 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2007
135views more  BMCBI 2007»
13 years 7 months ago
Detecting multivariate differentially expressed genes
Background: Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariat...
Roland Nilsson, José M. Peña, Johan ...
BMCBI
2008
107views more  BMCBI 2008»
13 years 7 months ago
A mixture model approach to sample size estimation in two-sample comparative microarray experiments
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
Tommy S. Jørstad, Herman Midelfart, Atle M....