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» Determining gene expression on a single pair of microarrays
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BMCBI
2010
130views more  BMCBI 2010»
13 years 7 months ago
A statistical approach to finding overlooked genetic associations
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...
Andrew K. Rider, Geoffrey Siwo, Nitesh V. Chawla, ...
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 7 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
BMCBI
2006
240views more  BMCBI 2006»
13 years 7 months ago
Statistical analysis of real-time PCR data
Background: Even though real-time PCR has been broadly applied in biomedical sciences, data processing procedures for the analysis of quantitative real-time PCR are still lacking;...
Joshua S. Yuan, Ann Reed, Feng Chen, C. Neal Stewa...
VIS
2005
IEEE
204views Visualization» more  VIS 2005»
14 years 8 months ago
Differential Protein Expression Analysis via Liquid-Chromatography/Mass-Spectrometry Data Visualization
Differential protein expression analysis is one of the main challenges in proteomics. It denotes the search for proteins, whose encoding genes are differentially expressed under a...
Lars Linsen, Julia Löcherbach, Matthias Berth...
BMCBI
2011
12 years 11 months ago
Inference of Chromosome-Specific Copy Numbers Using Population Haplotypes
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
Yao-Ting Huang, Min-Han Wu