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BMCBI
2010
133views more  BMCBI 2010»
13 years 11 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
BMCBI
2007
147views more  BMCBI 2007»
13 years 11 months ago
Improved residue contact prediction using support vector machines and a large feature set
Background: Predicting protein residue-residue contacts is an important 2D prediction task. It is useful for ab initio structure prediction and understanding protein folding. In s...
Jianlin Cheng, Pierre Baldi
BMCBI
2007
246views more  BMCBI 2007»
13 years 11 months ago
TomoJ: tomography software for three-dimensional reconstruction in transmission electron microscopy
Background: Transmission electron tomography is an increasingly common three-dimensional electron microscopy approach that can provide new insights into the structure of subcellul...
Cédric Messaoudi, Thomas Boudier, Carlos Os...
BMCBI
2005
104views more  BMCBI 2005»
13 years 10 months ago
Scoring functions for transcription factor binding site prediction
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
Markus T. Friberg, Peter von Rohr, Gaston H. Gonne...
DPD
1998
117views more  DPD 1998»
13 years 10 months ago
Solving Local Cost Estimation Problem for Global Query Optimization in Multidatabase Systems
To meet users’ growing needs for accessing pre-existing heterogeneous databases, a multidatabase system (MDBS) integrating multiple databases has attracted many researchers recen...
Qiang Zhu, Per-Åke Larson