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» Differential Algebra and System Modeling in Cellular Biology
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GCB
2004
Springer
101views Biometrics» more  GCB 2004»
14 years 1 months ago
Kleene's Theorem and the Solution of Metabolic Carbon Labeling Systems
: Carbon Labeling Systems (CLS) are large equation systems that describe the dynamics of labeled carbon atoms in a metabolic network. The rapid solution of these systems is the alg...
Nicole Isermann, Michael Weitzel, Wolfgang Wiecher...
JUCS
2010
215views more  JUCS 2010»
13 years 2 months ago
A Multidisciplinary Survey of Computational Techniques for the Modelling, Simulation and Analysis of Biochemical Networks
: All processes of life are controlled by networks of interacting biochemical components. The purpose of modelling these networks is manifold. From a theoretical point of view it a...
James Decraene, Thomas Hinze
BMCBI
2010
142views more  BMCBI 2010»
13 years 7 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
BMCBI
2007
124views more  BMCBI 2007»
13 years 7 months ago
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
G. Traver Hart, Insuk Lee, Edward M. Marcotte
BMCBI
2005
124views more  BMCBI 2005»
13 years 7 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...