Sciweavers

262 search results - page 11 / 53
» Directionality in protein fold prediction
Sort
View
BMCBI
2007
216views more  BMCBI 2007»
15 years 5 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
BMCBI
2007
93views more  BMCBI 2007»
15 years 5 months ago
SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
BMCBI
2007
144views more  BMCBI 2007»
15 years 5 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
ICML
2005
IEEE
16 years 6 months ago
Multi-class protein fold recognition using adaptive codes
We develop a novel multi-class classification method based on output codes for the problem of classifying a sequence of amino acids into one of many known protein structural class...
Eugene Ie, Jason Weston, William Stafford Noble, C...
BMCBI
2004
119views more  BMCBI 2004»
15 years 5 months ago
PASS2: an automated database of protein alignments organised as structural superfamilies
Background: The functional selection and three-dimensional structural constraints of proteins in nature often relates to the retention of significant sequence similarity between p...
Anirban Bhaduri, Ganesan Pugalenthi, Ramanathan So...