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» E-CAST: A Data Mining Algorithm for Gene Expression Data
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BMCBI
2007
182views more  BMCBI 2007»
13 years 9 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
CSB
2005
IEEE
146views Bioinformatics» more  CSB 2005»
14 years 2 months ago
Multi-Metric and Multi-Substructure Biclustering Analysis for Gene Expression Data
A good number of biclustering algorithms have been proposed for grouping gene expression data. Many of them have adopted matrix norms to define the similarity score of a bicluste...
Sun-Yuan Kung, Man-Wai Mak, Ilias Tagkopoulos
RECOMB
2006
Springer
14 years 9 months ago
Detecting MicroRNA Targets by Linking Sequence, MicroRNA and Gene Expression Data
MicroRNAs (miRNAs) have recently been discovered as an important class of non-coding RNA genes that play a major role in regulating gene expression, providing a means to control th...
Jim C. Huang, Quaid Morris, Brendan J. Frey
BMCBI
2004
158views more  BMCBI 2004»
13 years 8 months ago
A novel Mixture Model Method for identification of differentially expressed genes from DNA microarray data
Background: The main goal in analyzing microarray data is to determine the genes that are differentially expressed across two types of tissue samples or samples obtained under two...
Kayvan Najarian, Maryam Zaheri, Ali Ajdari Rad, Si...
BMCBI
2007
134views more  BMCBI 2007»
13 years 9 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...