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BMCBI
2010
13 years 2 months ago
2010
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
BIOINFORMATICS
2011
13 years 2 months ago
2011
Motivation: Analysis and intervention in the dynamics of gene regulatory networks is at the heart of emerging efforts in the development of modern treatment of numerous ailments i...
BMCBI
2011
13 years 2 months ago
2011
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
CORR
2010
Springer
13 years 2 months ago
2010
Springer
am analysis and has been widely studied. In this paper we consider this problem at the abstraction level of program schemas in which computations occur in the Herbrand domain of te...
JCC
2011
13 years 2 months ago
2011
: The Poisson–Boltzmann equation (PBE) is an established model for the electrostatic analysis of biomolecules. The development of advanced computational techniques for the soluti...