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CEC
2008
IEEE
13 years 7 months ago
Regulation of gene regulation - smooth binding with dynamic affinity affects evolvability
Abstract-- Understanding the evolvability of simple differentiating multicellular systems is a fundamental problem in the biology of genetic regulatory networks and in computationa...
Johannes F. Knabe, Chrystopher L. Nehaniv, Maria J...
ISCA
2007
IEEE
106views Hardware» more  ISCA 2007»
14 years 1 months ago
Architectural implications of brick and mortar silicon manufacturing
We introduce a novel chip fabrication technique called “brick and mortar”, in which chips are made from small, pre-fabricated ASIC bricks and bonded in a designer-specified a...
Martha Mercaldi Kim, Mojtaba Mehrara, Mark Oskin, ...
WWW
2003
ACM
14 years 8 months ago
Efficient URL caching for world wide web crawling
Crawling the web is deceptively simple: the basic algorithm is (a) Fetch a page (b) Parse it to extract all linked URLs (c) For all the URLs not seen before, repeat (a)?(c). Howev...
Andrei Z. Broder, Marc Najork, Janet L. Wiener
BMCBI
2010
156views more  BMCBI 2010»
13 years 7 months ago
Adaptive coarse-grained Monte Carlo simulation of reaction and diffusion dynamics in heterogeneous plasma membranes
Background: An adaptive coarse-grained (kinetic) Monte Carlo (ACGMC) simulation framework is applied to reaction and diffusion dynamics in inhomogeneous domains. The presented mod...
Stuart Collins, Michail Stamatakis, Dionisios G. V...
DAC
2008
ACM
14 years 8 months ago
Statistical modeling and simulation of threshold variation under dopant fluctuations and line-edge roughness
The threshold voltage (Vth) of a nanoscale transistor is severely affected by random dopant fluctuations and line-edge roughness. The analysis of these effects usually requires at...
Yun Ye, Frank Liu, Sani R. Nassif, Yu Cao