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» Efficient Seeding Techniques for Protein Similarity Search
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BMCBI
2007
133views more  BMCBI 2007»
13 years 9 months ago
Semantic integration to identify overlapping functional modules in protein interaction networks
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Young-Rae Cho, Woochang Hwang, Murali Ramanathan, ...
RECOMB
2006
Springer
14 years 9 months ago
Assessing Significance of Connectivity and Conservation in Protein Interaction Networks
Computational and comparative analysis of protein-protein interaction (PPI) networks enable understanding of the modular organization of the cell through identification of functio...
Mehmet Koyutürk, Ananth Grama, Wojciech Szpan...
ICDE
2003
IEEE
146views Database» more  ICDE 2003»
14 years 10 months ago
Distance Based Indexing for String Proximity Search
In many database applications involving string data, it is common to have near neighbor queries (asking for strings that are similar to a query string) or nearest neighbor queries...
Jai Macker, Murat Tasan, Süleyman Cenk Sahina...
BIBE
2006
IEEE
154views Bioinformatics» more  BIBE 2006»
14 years 3 months ago
Determining Molecular Similarity for Drug Discovery using the Wavelet Riemannian Metric
Discerning the similarity between two molecules is a challenging problem in drug discovery as well as in molecular biology. The importance of this problem is due to the fact that ...
Elinor Velasquez, Emmanuel R. Yera, Rahul Singh
GCB
2004
Springer
223views Biometrics» more  GCB 2004»
14 years 24 days ago
PoSSuMsearch: Fast and Sensitive Matching of Position Specific Scoring Matrices using Enhanced Suffix Arrays
: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs. In this paper, we present a new nonheuristic algorithm, ...
Michael Beckstette, Dirk Strothmann, Robert Homann...