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» Efficient protein alignment algorithm for protein search
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BMCBI
2010
104views more  BMCBI 2010»
13 years 8 months ago
Bidirectional best hit r-window gene clusters
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...
Melvin Zhang, Hon Wai Leong
BMCBI
2008
189views more  BMCBI 2008»
13 years 8 months ago
AnEnPi: identification and annotation of analogous enzymes
Background: Enzymes are responsible for the catalysis of the biochemical reactions in metabolic pathways. Analogous enzymes are able to catalyze the same reactions, but they prese...
Thomas D. Otto, Ana Carolina R. Guimarães, ...
BMCBI
2007
154views more  BMCBI 2007»
13 years 8 months ago
Inferring biological networks with output kernel trees
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
BMCBI
2007
133views more  BMCBI 2007»
13 years 8 months ago
Semi-supervised learning for the identification of syn-expressed genes from fused microarray and in situ image data
Background: Gene expression measurements during the development of the fly Drosophila melanogaster are routinely used to find functional modules of temporally co-expressed genes. ...
Ivan G. Costa, Roland Krause, Lennart Opitz, Alexa...
BMCBI
2010
154views more  BMCBI 2010»
13 years 6 months ago
Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation
Background: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gen...
Andreas Kowarsch, Florian Blöchl, Sebastian B...