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BMCBI
2010
97views more  BMCBI 2010»
13 years 6 months ago
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...
ICASSP
2009
IEEE
14 years 1 months ago
Microarray classification using block diagonal linear discriminant analysis with embedded feature selection
In this paper, block diagonal linear discriminant analysis (BDLDA) is improved and applied to gene expression data. BDLDA is a classification tool with embedded feature selection...
Lingyan Sheng, Roger Pique-Regi, Shahab Asgharzade...
JCP
2006
157views more  JCP 2006»
13 years 6 months ago
CF-GeNe: Fuzzy Framework for Robust Gene Regulatory Network Inference
Most Gene Regulatory Network (GRN) studies ignore the impact of the noisy nature of gene expression data despite its significant influence upon inferred results. This paper present...
Muhammad Shoaib B. Sehgal, Iqbal Gondal, Laurence ...
CIBCB
2007
IEEE
13 years 10 months ago
Genetic Regulatory Network Modeling Using Network Component Analysis and Fuzzy Clustering
Gene regulatory network model is the most widely used mechanism to model and predict the behavior of living organisms. Network Component Analysis (NCA) as an emerging issue for unc...
Fatemeh Bakouie, Mohammad Hassan Moradi
BMCBI
2007
148views more  BMCBI 2007»
13 years 6 months ago
Evaluation of gene-expression clustering via mutual information distance measure
Background: The definition of a distance measure plays a key role in the evaluation of different clustering solutions of gene expression profiles. In this empirical study we compa...
Ido Priness, Oded Maimon, Irad E. Ben-Gal